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Real Madrid's quest for a 16th UEFA Champions League title continues with a tricky fixture against Italian giants Juventus on Wednesday. Los Blancos are off to a hot start in this year's continental showcase, beating Marseille 2-1 on Matchday 1 before steamrolling Kairat Almaty 5-0 in Kazakhstan, which included a hat-trick from Kylian Mbappé. Madrid currently sit in second place in the UCL league phase standings, tied with leaders Bayern Munich on points (6) and goal differential (6). Xabi Alonso's troop is fresh off a nervy 1-0 win over city rivals Getafe, thanks to an 84th minute strike by Mbappé. The Royal Whites maintained their lead at the top of the La Liga table, two points clear of FC Barcelona after nine games. The eternal rivals are set to clash this weekend in the season's first El Clasico at the Santiago Bernabeu. Juventus, meanwhile, are still looking for their first win in this year's competition after dramatic draws with Borussia Dortmund and Villareal in the first two matchdays. The Old Lady currently sits in 23rd place in the league phase standings, just one spot clear of the elimination zone. Juventus are coming off a difficult 2-0 loss away to Como, and are winless in their six games in all competitions. Real Madrid and Juventus have faced each other 21 times in the Champions League, with the Italians claiming 10 of those meetings — one more than their Spanish rivals. They last faced off in the quarter-finals of the 2017-18 campaign, with Madrid claiming a 4-3 aggregate win after beating Juventus in the final the previous year. Where to Watch Real Madrid vs Juventus When: Wednesday, October 22 – 3PM ET / 12PM PT Where: Estadio Santiago Bernabeu, Madrid Where to watch in the United States: CBS Sports, Paramount+ Real Madrid vs Juventus Betting Odds Real Madrid to win: -230 Draw: +370 Juventus to win: +550 Both teams to score (Yes/No): -142 / +112 Over/Under 3.5 goals: +144 / -178 Kylian Mbappé first goalscorer: +290 Dusan Vlahovic anytime goalscorer: +240 Vinicius Jr. anytime goalscorer: +130 Odds courtesy of FanDuel. Juventus Team News and Predicted Lineup Jonathan David is expected to lead the attacking line for Igor Tudor's side on Wednesday, looking to re-create the same magic that pushed him to score the winner over Real Madrid when he played for Lille around this time last year. Kenan Yildiz and Francisco Conceicao are likely to play just behind the striker, with Joao Mario and Andrea Cambiaso acting as flying wing-backs on either flank. Tudor likes to play with three at the back, but Juventus will have to make up for the loss of defensive stalwart Bremer, as the Brazilian continues to recover from a knee injury. Expect Englishman Lloyd Kelly to fill in a one of the center-backs. Juventus predicted lineup (3-4-2-1): Michele Di Gregorio (GK) – Pierre Kalulu, Federico Gatti, Lloyd Kelly – Joao Mario, Manuel Locatelli, Khephren Thuram, Andrea Cambiaso – Francisco Conceicao, Kenan Yildiz – Jonathan David. Real Madrid Team News and Predicted Lineup Xabi Alonso will be missing several key defenders on Wednesday, as each of Antonio Rudiger, Dani Carvajal, Dean Huijsen, Trent Alexander-Arnold and Ferland Mendy remain sidelined with injuries. Federico Valverde will have to deputize at right-back once again, while French duo Aurelien Tchouameni and Eduardo Camavinga make up the midfield duo. Teenage sensation Franco Mastantuono is expected to get another start, complimenting superstar forwards Vinicius Jr. and Kylian Mbappé in attack.
