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Omeprazole ranks amongst Britain's most frequently prescribed medications, with latest statistics revealing 73 million NHS prescriptions for proton pump inhibitors (PPIs), such as Omeprazole, were issued across England during 2022-23. Separate data indicates that roughly 15% of the population relies on PPI treatment. PPIs are medications that reduce stomach acid production. They function by blocking the proton pumps, enzymes situated in the stomach lining that generate acid. This alleviates problems including acid reflux and heartburn. Other health conditions managed by PPIs encompass indigestion, stomach ulcer recovery, gastro-oesophageal reflux disease (GORD), and gastroesophageal reflux disease (GERD). The medication can also be utilised alongside antibiotics to combat the stomach bug Helicobacter pylori. Widely-used PPIs encompass Omeprazole (Prilosec), Esomeprazole (Nexium), Lansoprazole (Prevacid), Pantoprazole (Protonix), and Rabeprazole (AcipHex). Whilst they prove successful, especially for prolonged treatment courses, there are possible dangers linked to extended usage, reports the Mirror . The NHS has issued a caution regarding this matter on its website. The guidance states: "Do not take omeprazole for longer than two weeks if you bought it without a prescription. See a GP if your symptoms get worse or do not get better." Long-term use of PPIs has been linked to an increased risk of a bacterial infection known as Clostridioides difficile. This bacterium can cause an infection in the intestines, leading to diarrhoea and other symptoms such as abdominal pain and fever. Clostridioides difficile typically causes illness when antibiotics disrupt the balance of normal gut bacteria, allowing it to grow and produce toxins. In most individuals, Clostridioides difficile coexists harmlessly with other bacteria in the intestines. However, when antibiotics wipe out the beneficial bacteria, they can rapidly multiply. The toxins produced irritate the colon, resulting in infection symptoms. Clostridioides difficile can be triggered by medication disrupting the natural gut flora. It can also spread through spores that survive on contaminated surfaces. It primarily affects at-risk groups, including the elderly and those with weakened immune systems. Join the Daily Record's WhatsApp community here and get the latest news sent straight to your messages. Omeprazole usually comes in tablet, capsule, and liquid form for ingestion. Some tablets can be dissolved in water. The dosage and length of treatment depend on the specific type of omeprazole you are using and the reason for its use. It is generally taken once or twice daily. Some individuals may only need it for a few days, whilst others might require continued use for several weeks, months, or even years. Always check the packaging or leaflet that comes with your medication. If you're unsure about how to take it or experience any problems, seek advice from a pharmacist or doctor. It adds: "Ask a pharmacist for advice if you have problems swallowing pills or capsules. They may be able to suggest different ways to take your medicine." Side effects of omeprazole:. Like all medicines, omeprazole can cause side effects, but not everyone gets them. Common side effects of omeprazole include:. The NHS says: "Omeprazole will not usually affect your ability to drive, ride a bike or use machinery. But if you feel dizzy or have problems with your vision after taking it, wait until you no longer have these side effects." Don't miss the latest news from around Scotland and beyond - Sign up to our daily newsletter here.
