Copyright Men's Journal

Longevity has officially gone mainstream, and it’s backed by science. A JAMA Internal Medicine review found that cardiorespiratory fitness, muscle strength, and metabolic health markers are directly associated with lower all-cause mortality risk, which is fueling the surge of preventive care investment among high performers. That may explain why executives from Silicon Valley to New York are investing up to $15,000 for full-body preventive diagnostics at Biograph, a new elite longevity clinic in San Mateo and New York. The promise: identify disease long before symptoms show up. What You Get From a Full-Day Longevity Evaluation At Biograph, the standard annual physical is replaced by a six-hour, lab-grade evaluation inside a spa-like, luxury medical setting. Members move through more than 20 advanced tests—whole-body MRI, coronary CT for silent plaque, DEXA for bone density, VO₂ max treadmill testing, metabolic blood work, cognition markers, and video movement analysis. “This is not reactive healthcare,” says Michael Doney, M.D., Biograph’s Executive Medical Director “This is proactive detection—before it becomes an emergency.” According to Dr. Doney, roughly one in six clients uncover something serious, like early cancer or a silent heart blockage, with no outward symptoms. Membership ranges from $7,500 to $15,000 depending on the level of ongoing support. Why High Performers Are Betting on Prevention Now With longevity evangelists like Bryan Johnson and Gary Brecka pushing ultra-optimized aging into the mainstream, preventive screening is no longer fringe biohacking—it’s becoming a competitive corporate wellness arms race. And Peter Attia, M.D., co-founder of Biograph and best-selling author of Outlive: The Science and Art of Longevity, has helped drive a newer definition of longevity: not just adding years to your life, but protecting the pillars that determine how well you can live those years—cardiac function, metabolic health, brain aging, and cancer risk. It’s also backed by research. A 2025 review published in British Journal of Sports Medicine found that higher cardiorespiratory fitness and greater muscle strength meaningfully reduce all-cause mortality risk. High performers see the message clearly: investing in prevention now is a bet on more functional years later—not just another stack of health metrics. What You Can Do Today to Improve Longevity Even before stepping into a high-end longevity clinic, experts say you can start building a stronger foundation for long-term health with simple, evidence-backed habits today. Strength train three to four days weekly—muscle is one of the strongest aging buffers. A space-saving setup like the REP Fitness Apollo Half Rack lets you build serious brawn at home without dedicating an entire room to equipment. Improve VO₂ max with regular interval work and steady cardio. Breathable training apparel from Reigning Champ can keep you comfortable during tougher conditioning sessions. Prioritize whole foods, adequate protein, and balanced carbs. Chef-crafted meal services, like CookUnity, make it easy to stay consistent without the prep. Schedule targeted screenings—especially if certain diseases run in your family. Bottom line: Biograph is turning prevention into a premium product. But the longevity science is clear—many of the same benefits can start right now, without a six-hour clinic day.