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Made in Chelsea star Sam Vanderpump has been diagnosed with end-stage liver disease and urgently requires a transplant. Doctors have informed the 28-year-old reality star that his life expectancy is as short as four years without the vital surgery. Vanderpump suffered a near-death experience last Christmas when sepsis, caused by a genetic disease, led to liver and kidney failure. He is currently expecting his first child with his fiancée, Alice Yaxley, whom he proposed to following a previous health scare. End-stage liver disease is a condition where the liver is irreparably damaged, with symptoms including fatigue, jaundice, swelling, and bruising.