Copyright Variety
If you purchase an independently reviewed product or service through a link on our website, Variety may receive an affiliate commission. When Juxtapose Studio founder Luke Anderson consulted a medium on the advice of his assistant, he didn’t expect it to change his career — or his life. At the time, he was newly divorced, chain-smoking indoors, and, by his own admission, “a little lost.” “I was in the middle of a messy corporate entanglement and didn’t really know what to do next,” he recalls. “My assistant told me to call a medium. So, I get on the phone, and she tells me to unmerge two companies and go into business with Patricia Arquette. I said, ‘The medium from television?’ And she said, ‘Yeah, that’s the one.’” Thankfully, Anderson already had Arquette’s phone number from working together on a campaign for his former company, the weed soda brand Cann, so he called her up. Two years later, that psychic suggestion has materialized into Juxtapose Studio — a creative agency officially launching into the public eye this week with Arquette as a founding advisory partner and director. Co-founded by Anderson alongside Amanda Goldfine and Hector Keate, the studio has quietly built a reputation for its offbeat, pop culture-savvy brand campaigns that pair unexpected celebrity talent with humor and social commentary. The creative agency has worked with brands like Dunkin’, DICK’S Sporting Goods, Sonic, Arby’s and Buffalo Wild Wings, and has produced viral campaigns featuring everyone from Will Arnett and Kathryn Hahn to Malin Åkerman and The Jonas Brothers. Most recently, they launched a “Wicked: For Good” Dunkin’ campaign with Jonathan Baily and Cynthia Erivo. Beyond branded work, Juxtapose is also expanding into original film and television, developing projects like “I’m Gonna Kill You” from Andrew Chappelle and “FLEW” from Jorey Worb, alongside a slate of scripted series and features slated for 2026. As a partner, Arquette will lend advice and perspective drawn from decades in entertainment. “Sometimes we’ll all pitch commercial ideas or talk about people’s skills and strategies,” she tells Variety. “The team is incredibly funny and sarcastic and very cutting-edge. They have a different relationship with messaging and new technologies, and I think that’s fascinating.” She adds that Juxtapose stands out because “they’re sardonic, and they have a funny way of looking at the world. They understand the humor of young people, they appreciate the brand but are also willing to kind of turn things on their head a bit. There are moments where you want to celebrate the inside joke with your audience, where you want to grab onto things that matter to your generation.” The studio, which now counts multiple high-profile directors and brand partners, was founded on the belief that advertising can feel as artful and self-aware as the entertainment it borrows from. “Patricia has been a North Star on that front,” Anderson says, noting Patricia’s outspokenness on the use of AI in the arts. “There’s no substitute for a heart and a soul. AI can do a lot to optimize workflows, but creative that has a pulse, it’s not quite able to do that.” Arquette agrees that keeping the human element front and center is essential. “You can’t leave that to AI,” she says. “Half the time it’s lying to you and it’s wrong. You still need people with values, and I think Luke and Hector are really committed to that.”
