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People taking the painkiller tramadol for extended periods could be at risk of a significant side effect. Tramadol, part of the opiate family, is often prescribed to treat moderate to severe pain, such as post-injury or post-operation discomfort. Due to its strength and effectiveness in managing pain, doctors may prescribe tramadol when other painkillers prove ineffective. It's typically dispensed as a tablet or capsule, but can also be administered as a liquid drop or injection, the latter usually in hospital settings. In some instances, long-term use of tramadol may be necessary, particularly for those dealing with chronic pain from a health condition. While this can help manage daily pain, it is crucial to be aware that it may heighten the risk of unpleasant side effects. The NHS has highlighted the dangers of long-term tramadol use, including hyperalgesia. This condition, which can make individuals more sensitive to pain, means that normal pain can feel much more severe or excessive. If you experience this, your doctor may decide to gradually reduce your tramadol dose to help alleviate your symptoms. As a painkiller, tramadol can lead to the body developing a tolerance if it's used over an extended period. This means that you may need to increase your dosage progressively to achieve the same relief as before. Given that tramadol is an opiate, there is a risk of addiction, particularly if it is used for a long duration. Signs of tramadol addiction could include struggling to stop its use or taking it more frequently than needed. You might also experience withdrawal symptoms if you abruptly cease its use, which could involve feelings of anxiety and restlessness. If this occurs, your GP may want to reassess your medication to ensure you are only receiving the necessary dose to manage your pain. Full details of the side effects surrounding tramadol can be found on the NHS website here.