NFL picks, Week 8 against the spread spread, money-line, over/under best bets from self-learning AI
NFL picks, Week 8 against the spread spread, money-line, over/under best bets from self-learning AI
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NFL picks, Week 8 against the spread spread, money-line, over/under best bets from self-learning AI

🕒︎ 2025-10-21

Copyright CBS Sports

NFL picks, Week 8 against the spread spread, money-line, over/under best bets from self-learning AI

Aaron Rodgers spent the first 18 years of his future Hall of Fame career with the Green Bay Packers. His career comes full circle in NFL Week 8 when his Pittsburgh Steelers take on the Packers in Pittsburgh. It will be the first time he has faced the team that drafted him in the first round of the 2005 NFL Draft. The Packers (4-1-1) lead the NFC North, while the Steelers (4-2) are on top of the AFC North. Green Bay enters as a 3-point favorite. Another matchup involving contenders sees the Buffalo Bills (4-2) visiting the Carolina Panthers (4-3). The Bills are -7.5 favorites, one of five games with spreads of -7 or more. The largest is Tennessee at Indianapolis (-14). How should you handle those NFL games and optimize what to bet on NFL in Week 8? Before making any Week 8 NFL picks or Week 8 NFL score predictions, you need to see the NFL against the spread, over/under and money line predictions powered by the self-learning SportsLine AI. New users can target the DraftKings promo code, which offers $300 in bonus bets if your bet wins + 3 months of NBA League Pass: Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team's historical data and then quantitatively evaluating the strength of the opponent's defense by assigning a numeric value out of 100 called a matchup score. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. SportsLine's AI PickBot has hit more than 2,000 4.5- and 5-star prop picks since the start of the 2023 season. For Week 8 NFL betting, the AI PickBot has evaluated the NFL odds and provided NFL betting picks for all 13 games. You can only see the AI predictions for the Week 8 NFL schedule here. New users can also target the latest Underdog promo code, good for $100 in site credits when you play $5 with the promo code CBSSPORTS2 in select states. Top Week 8 NFL AI picks After analyzing every game in Week 8, the AI says the Colts (-14, 47) cover comfortably against the Titans. Daniel Jones has dominated in his first year with Indianapolis. In seven starts with the Colts, he has completed 152 of 214 passes (71%) for 1,790 yards and 10 touchdowns with just three interceptions. He has also rushed 29 times for 83 yards and four scores. Jones had spent his first six seasons with the New York Giants. He was released late last November and signed as a free agent with the Minnesota Vikings, but did not see the field. This offseason, he joined the Colts as a free agent. He has thrown for 225 or more yards in five of seven games. In a 29-28 win over the Denver Broncos on Sept. 14, he completed 23 of 34 passes for 316 yards and one touchdown. He also rushed for a score. SportsLine AI rates a Colts spread cover as an A pick and also predicts a 36-18 win on average. See its other Week 8 football predictions and football picks at SportsLine. How to make Week 8 NFL picks In addition, the AI PickBot has generated well over 20 highly-coveted A+ picks for Week 8. You need to see the AI's NFL picks before making any Week 8 NFL bets of your own. You can only see them at SportsLine.

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