Huntington’s disease, a deadly degenerative illness, has been treated for the first time in a revolutionary gene therapy trial. The disease is a hereditary illness, typically appearing in adults in their 30s and 40s. The symptoms include mood swings, anger, depression, uncontrolled jerky movements, dementia, and paralysis. There has been no cure or way to minimize its progression. The trial concluded that the treatment had slowed the progression of Huntington’s disease by an average of 75 percent. Additionally, the medication helped protect neurons, resulting in fewer signs of cell death. Sara Tabrizi, director of the University College London’s Huntington’s disease centre, reports that the drug will help people work and live independently for longer. Tabrizi said, “We now have a treatment for one of the world’s more terrible diseases. This is absolutely huge. I’m really overjoyed.” There are 20,000 people in the U.K. who carry the gene, but only a fifth of those families conduct genetic testing. Tabrizi claims that these revolutionary developments in medication will prompt “more people to come forward for the genetic test because there’s a treatment.”
Matthew McConaughey’s mother had a strange request following her husband’s death after they had sex. The Dallas Buyers Club actor’s mother, Mary Kathleen “Kay” McConaughey, wanted his father carried out “in his birthday suit” after his fatal heart attack, McConaughey wrote in his 2020 book, Greenlights. McConaughey, 55, recalled his mom’s words as his father, James Donald McConaughey’s body was taken out of their house covered in a sheet. McConaughey said his mom pulled off the sheet, saying “‘That’s Big Jim, he’s gonna go out how he went. Don’t be trying to cover up how he went out. He’s in his birthday suit and he’s right there. Don’t be covering that man up!’” James always wished to die making love to Kay, McConaughey said in a Saturday interview with The Guardian about his new book, Poems & Prayers. McConaughey dad died back in 1992 when he died at the age of 62. The couple had a turbulent relationship in which they were “married three times, divorced twice,” the Interstellar actor said. McConaughey speculated that his parents “just needed some breaks for each other.”
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Sleep can be hard to come by these days. From city noise and snoring partners to late-night scrolling and spiraling thoughts, there’s a lot that can get in the way of a good night’s rest. In fact, research suggests that one in three adults doesn’t get enough sleep. (Hello, fellow insomniacs!) Luckily, you don’t have to accept exhaustion as your default—Ozlo Sleepbuds can help improve sleep hygiene sans habit-forming treatments or sleeping in separate rooms (aka ‘sleep divorce’).
Developed by former Bose engineers, Ozlo Sleepbuds are a science-backed wearable engineered to help you fall asleep faster and stay asleep longer every night. Unlike earplugs or other sleep aid gadgets, Ozlo doesn’t just block sound. Instead, these earbuds are specifically designed to support a restful sleeping experience.
Ozlo Sleepbuds
Comes with a free one-year subscription to Calm Sleep Premium.
In addition to premium noise-masking capabilities, the buds feature biometric sleep detection that senses when you fall asleep and transitions from whatever audio you were listening to—yes, you can stream from all your favorite apps—into built-in soundscapes engineered for rest. Plus, the side sleeper-friendly Sleepbuds are designed for all-night comfort, so you can drift off without distraction until the gentle in-ear alarm wakes you (not your partner) up in the morning.
From now through the end of Sept., you can elevate your sleeping experience for less with a perk. Save $50 on your pair of Ozlo Sleepbuds and unlock a year of free access to Calm Sleep Premium, a mindfulness-focused app featuring more than 300 hours of sleep content from leading experts. Dreams really do come true.
A vast sinkhole, estimated to be 160 feet deep, enveloped a large section of road in Bangkok on Wednesday, swallowing three cars whole and forcing locals to evacuate. Footage of the dramatic moment, believed to have been triggered by the construction of an underground railway, saw the road’s surface slowly subsiding, dragging down electricity poles and water pipes while nearby drivers frantically tried to escape the growing chasm. Although there were no casualties, a tow truck belonging to a nearby police station was claimed by the sinkhole, along with two more vehicles that were unable to escape in time. A hospital that bordered the chasm was left structurally intact, but it announced that it would be closing its outpatient services for two days until the situation was stabilized. Officials have cut off water and electricity in the area to prevent further damage. Bangkok officials say they are working to repair the hole as quickly as possible, due to fears that heavy rainfall caused by the ongoing monsoon season could exacerbate the situation.
Fans attending the Ryder Cup’s opening day on Friday have been prohibited from bringing range finders into the event due to “enhanced security measures” due to President Donald Trump’s plans to attend. The ban on range finders, which are commonly used to map out how far the ball is from the hole, comes a little over a year after the Pennsylvania assassination attempt of Trump. About 20 minutes before the Butler rally began, Trump’s would-be assassin Thomas Matthew Crooks was spotted by an officer using a range finder. The Ryder Cup has also banned people in the first tee grandstand or clubhouse area from bringing large umbrellas, portable folding chairs, torch-style lighters, large vaping devices, metal/hard plastic insulated beverage containers, laptops and tablets. Fans should also expect to go through TSA-style screening points at the entrance and throughout the event itself. To accommodate these additional measures, Ryder Cup officials have decided to open the gates at 5 a.m. on Friday and told fans that they should expect delays due to increased security. All of this prep comes after Trump’s arrival at the U.S. Open caused the men’s singles final match to be delayed by nearly 50 minutes.
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Turn your holiday countdown this year into something a little naughtier (and more fun) with Lovehoney’s Advent calendars. A spicy spin on the class tradition, these calendars are an erotic journey of passion, play, and connection. Choose from five tantalizing options, each loaded with toys and treats to keep things steamy all winter long. The ultimate pick? The Couples Calendar. With 24 luxe goodies—think card games, blindfolds, and whips—it’s full of ways to turn everyday into a new adventure with your partner.
Lovehoney Couple’s Advent Calendar (24 Day)
The standouts are definitely the Womanizer Classic 2 and the We-Vibe Sync Lite—worth $260 alone. The Womanizer Classic 2 is a clitoral stimulator that uses air to deliver a sucking sensation. The We-Vibe Sync excels at couples play. Hands-free, wearable, and flexible, it delivers pleasure to both partners all at once. Plus, with the app, you (or your partner) can get even naughtier, whether you’re in the same room or across the house. As always, Lovehoney ships its items in discreet packaging to keep your purchase confidential.
A plane carrying the Spanish minister of defense has suffered from a suspected Russian GPS jamming attack. Officials from the Iberian nation said the Airbus A330 carrying Margarita Robles, 68, encountered what the Daily Mail described as a “disturbance” while traveling to Lithuania. She was bound for Siauliai airbase in the north of the country, where she was scheduled to meet her counterpart, Dovile Sakaliene. During the flight, the plane flew over the Russian enclave of Kaliningrad, which is separated from the rest of Russia by the NATO member states of Lithuania and Latvia. A Spanish defense ministry spokesperson said, “There has been an attempt to disrupt the GPS signal, but as our aircraft has an encrypted system, it was not affected.” The incident comes on the back of several flashpoints connected to Russia. Between 19 and 23 drones were shot down in Polish airspace. A jet carrying European Commission President Ursula von der Leyen to Bulgaria suffered GPS disruption and had to make an emergency landing. Sky News reports the Spanish plane was also carrying the families of NATO pilots defending the alliance’s eastern border.
Cleveland Guardians designated hitter David Fry was hospitalized Tuesday night after being struck in the face by a 99 mph fastball during his team’s 7-3 win over the Detroit Tigers. The incident came in the sixth inning when Fry, 29, squared around to bunt on a pitch from the Tigers’ Tarik Skubal. The ball sailed past Fry’s bat and hit him directly in the face, sending him crashing to the ground as medical staff rushed to his aid. Fry was able to stand and walk to a cart before being transported first to Lutheran Medical Center and then to Cleveland Clinic’s main campus for further evaluation and overnight observation, according to Guardians reporter Tim Stebbins. The team confirmed the updates on its official social media account. “He’s getting tested. He’s stayed conscious the whole time,” Guardians manager Stephen Vogt told reporters after the game. “Definitely some injuries there. So I’ll give you an update tomorrow.” Skubal appeared visibly shaken as Fry was treated on the field, pacing the mound until play resumed. Afterward, he told reporters it was “really tough” to see. “I’ve already reached out to him… I just want to make sure he’s all right,” Skubal said.
A vocal critic of the Kennedy Center’s leadership claimed that President Donald Trump’s supporters conspired to harass her during her show. Guitarist Yasmin Williams said there was a coordinated effort to boo and heckle her, alleging that audience members “seemed to be there to intimidate me.” She clashed with the center’s Trump-appointed president, Richard Grenell, in April over his abandonment of DEI programming. The Washington Post reports that members of conservative LGBT group Log Cabin Republicans D.C. attended the first 15 minutes of her free show Thursday ahead of a monthly meeting that had been moved two days before to the center’s rooftop terrace. An email from the group, posted on her Instagram, encourages members to attend the show of the “liberal guitarist” who “is apparently a vocal opponent of President Trump.” Its author, Andrew Minik, also said there would be an open bar, adding, “Let’s make sure the audience is filled with patriots.” The disruption only included brief boos when the 28-year-old said to open her show, “I do not support the new board at all,” “anyone affiliated with the Trump administration,” or “Ric Grenell.” Kennedy Center spokesperson Roma Daravi told the Post: “This is an absolutely ridiculous claim. There was no coordinated effort by the Kennedy Center. Grenell had no involvement. We did not even know they were coming.” The Post reports that staff escorted Williams from the venue via a “secret door” afterward. The Daily Beast has contacted Log Cabin Republicans for comment.
Donald Trump’s approval rating has dipped further as Americans grow increasingly concerned about his handling of the economy and ability to contain the rising prices of everyday goods. A poll conducted by Reuters over the weekend showed the president’s overall performance rating had dropped from 42 to 41 percent, with 54 percent of respondents saying they believed the economy was on the wrong track—up from 52 percent in July. Just 35 percent approved of Trump’s handling of the economy, and 28 percent believed he was doing a good job of tackling the ongoing cost-of-living crisis. Trump’s approval is buoyed by a general satisfaction over his immigration policies, which still poll high among Republican voters, along with his tough approach to handling crime. Following the killing of Charlie Kirk, a majority of Americans now believe political extremism to be one of the country’s most significant problems, which Trump has claimed comes “largely from the left.” Yet despite general dissatisfaction with the president’s handling of the economy, voters still believe the Republicans have a better plan for handling the markets than the Democrats, by a margin of 34-24 percent.
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With fall on the horizon, it’s time to get back into jackets. There’s truly nothing like a good jacket worn on a crisp autumn day, but finding the right one is actually harder than it seems. I’ve never been much of a jacket kind of guy, but then I came across a really special jacket from Huckberry, and now I understand why it’s a bestseller. Flint & Tinder’s Waxed Trucker Jacket is the best jacket in my closet—and frankly, the best thing I own at this point. This lightweight yet rugged jacket has only gotten better and better the more I’ve worn it, and I’ve owned it for a few years now. The waxed canvas feels soft and supple to the touch, and when I throw it on, it isn’t restricting at all.
Flint & Tinder’s Waxed Trucker Jacket
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What’s cool is with every movement, I can feel myself making a mark on the jacket—whether I’m leaning over to tie my shoes or hopping on my bike—I can feel the jacket getting more and more comfortable and broken in. The exterior is made with a weather-resistant waxed Martexin sailcloth; the interior is fully lined with a blanket-worthy lining, so you get the best of both worlds. It’s extremely stylish and goes with anything I wear it over, like sweaters, tees, and even button-downs. Right now, it comes in several different colors, but personally, I’m partial to the Havana brown. Slowly, this isn’t just becoming the best jacket in my closet, but it’s the only one I ever want to wear—that’s how good it is.
Claudia Cardinale, the acclaimed Italian actress whose captivating beauty and talent defined some of the most celebrated European films of the 20th century, has died, her agent has confirmed. Famed for her roles in films such as The Pink Panther, Once Upon a Time in the West, and The Professionals, Cardinale, 87, was celebrated as one of the greatest actresses of her generation, turning down lucrative roles in major Hollywood productions to protect her independence and maintain a presence in the European market. Often cast as a femme fatale type due to her deep, heavily-accented French-Italian dialect, she worked on over 100 films with some of the biggest names of her era. Tributes poured in for the screen legend, including from French President Emmanuel Macron. Italian Culture Minister Alessandro Giuli hailed her as “one of the greatest Italian actresses of all time,” praising her “exceptional talent.” In 2000, Cardinale was named a UNESCO ambassador for women’s rights, and received a lifetime achievement award at the Berlin Film Festival in 2002. “I’ve lived more than 150 lives, prostitute, saint, romantic, every kind of woman, and that is marvellous to have this opportunity to change yourself,” she said.
Parents of children killed or still missing after Texas’ July 4 floods blasted Camp Mystic this week after learning one of its locations will reopen next summer. “The truth is, Camp Mystic failed our daughters,” said Cici Steward, whose 8-year-old, Cile, remains missing. “For my family, these months have felt like an eternity. For the camp, it seems like nothing more than a brief pause before business as usual. Camp Mystic is pressing ahead with reopening, even if it means inviting girls to swim in the same river that may potentially still hold my daughter’s body.” According to letters obtained by CBS News and KHOU 11, Camp Mystic Cypress Lake will reopen next year, even though the bodies from the floods have not all been recovered. The Christian girls’ camp’s Guadalupe location—where 27 campers and counselors drowned when “catastrophic” rains swept through—was deemed too damaged to reopen in 2026. The letters also revealed plans for a memorial to honor victims. But Blake Bonner, father of 9-year-old Lila, said families “were not consulted about and did not approve this memorial.” By July 14, Hill County’s official death toll from the floods had reached 132, with more than 100 still missing.