By Gayatri Guha

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Tamil Nadu’s startup story has always been rooted in solving real problems. As the state races toward its vision of becoming a Top 20 Global Startup Hub by 2032, a new wave of founders is proving that innovation thrives at the intersection of technology and purpose. From industrial safety and preventive healthcare to financial inclusion and child development, these ventures show how Tamil Nadu’s entrepreneurial energy is reshaping lives across sectors.

At the Tamil Nadu Global Startup Summit (TNGSS) 2025, this momentum takes center stage with startups like Quantic Tech, Diagno Intelligent Systems, IppoPay, and Kathaipetti, each addressing challenges that touch millions while building scalable, sustainable businesses.
Eyes on every corner: Quantic Tech’s AI for industrial safety
Industrial accidents are preventable, yet they continue to claim lives and disrupt operations. Chennai-based Quantic Tech Analysis, founded in 2021 by Senthil Kumar and Sravani Rao, is tackling this challenge head-on with AI-driven video analytics that transform existing CCTV infrastructure into intelligent safety systems.

The platform monitors industrial environments in real time, detecting safety violations, quality defects, and process deviations across chemical plants, steel mills, construction sites, and oil and gas facilities. Unlike traditional systems that rely on manual oversight, Quantic’s software delivers automated alerts and actionable insights, making safety scalable and cost-effective.

“At Quantic, we believe AI is not just about automation, but about saving lives, reducing risks, and building a safer tomorrow for industries,” Kumar says.

The impact has been tangible. Quantic is the only startup in India to secure a single-party tender from a government PSU, Bharat Petroleum Corporation Limited, and now works with three Fortune 500 companies. Recognition from the World LPG Association and TiE Tamil Nadu validates its approach, while the company’s expansion into the Middle East and Europe signals global ambition. With plans to scale to over 100 industrial plants and establish an entity in Oman, Quantic is positioning Tamil Nadu as a hub for AI-powered industrial intelligence.
Hidden in plain sight: Diagno’s breakthrough in bone health screening
Osteoporotic fractures cause 8.9 million cases annually, with over half projected to occur in Asia by 2050. Access to DXA bone densitometers, the gold standard for diagnosis, is critically low. India has just 0.26 DXA units per million people, compared to 12 to 24 in developed nations. One person dies every ten minutes from osteoporotic fractures, yet early detection remains out of reach for most.

Chennai-based Diagno Intelligent Systems, founded by Dr Felix Enigo and Dr Anburajan Mariamichael, is changing this with iOsteoporos Screen, an AI-powered Software as Medical Device (SaMD) that transforms routine chest X-rays into a low-cost, scalable screening tool for osteoporotic fracture risk.

Using patented AI that integrates clavicle radiogrammetry, bone features, and patterns, the platform enables earlier detection of fracture risk by 30-50 percent at just Rs 100 per test, a 95 percent cost reduction compared to DXA. The system is accessible via a mobile app, cloud-based SaaS, and desktop. It integrates with PACS and other hospital systems, enabling frontline health workers to use it without specialized training. A PCT application has been published, and a US IDS filing is underway. Validation was conducted in two Tier-1 hospitals under a CDSCO test license.

Routine chest X-rays hold untapped potential. We are unlocking them with advanced AI to make osteoporotic fracture risk screening affordable, scalable, and lifesaving,” Enigo says.

With over 100 million routine chest X-rays conducted annually in India, the platform’s potential reach is staggering. Diagno has completed pilot trials in two hospitals, with two more in the pipeline, and secured seeds grants and funds totaling Rs 123.72 lakh from BIRAC and StartupTN. Shortlisted for the Mayo Clinic Platform Accelerate Program, the company is advancing toward full regulatory approval and global deployment.
Credit where it’s needed: IppoPay’s financial revolution for small merchants
For millions of small merchants across Tamil Nadu’s Tier II, Tier III, and rural markets, access to formal credit has long been a barrier. Chennai-based IppoPay Technologies, founded in 2020 by Mohan K and Jaikumar R, is rewriting this story with a credits-first digital payments and lending platform designed specifically for underserved merchants. The platform enables UPI payments while providing instant, collateral-free credit powered entirely by digital payment data.

What sets IppoPay apart is its transparency. No hidden fees, no paperwork, and full automation ensure merchants know exactly what they are paying and receiving. The entire experience, from onboarding to repayment reminders, is vernacular and built around the daily rhythm of small businesses.

“IppoPay’s story is about possibility. We started with the smallest merchants, and their trust has carried us forward. Our vision now is larger, but our promise remains the same: to build financial solutions that serve with dignity, transparency, and trust,” Mohan says.

In just 24 months since launching lending, IppoPay has disbursed Rs 120 crore with an annual run rate of Rs 250 crore. The company has reached over 500,000 merchants across Tamil Nadu, achieving 100 percent digital collections with zero cash handling. Recognition as Entrepreneur of the Year in Financial Services at the Global Business Conclave 2025 and inclusion in Ananda Vikatan’s top 10 youngsters of Tamil Nadu underscore its impact.

IppoPay is now preparing to roll out its UPI Third-Party Application Provider (TPAP) platform, built in Tamil Nadu for Tamil Nadu, before scaling across India.
Stories that sound like home: Kathaipetti’s voice-led companion for children
In an age of hyper-stimulating content, finding age-appropriate, culturally rooted storytelling for children has become a challenge. Chennai-based Kathaipetti, founded by Nithya Ganapathisubramanian, Harikrishnan Prakasam, and their friends as co-founders, began as a parent’s search for a gentler alternative and evolved into an AI-enabled, personalized story companion for children aged 3 to 13.

The platform lets families clone familiar voices, whether a parent, grandparent, or even the child, to narrate tales. Characters can be customized, and the app progressively tailors the story experience so it feels made just for the listener. The result is a safe, screen-light, habit-forming storytelling companion that fits naturally into a child’s routine.

In its first month after launch on Android, Kathaipetti crossed 18,000 users. Now live on both iOS and Android, the app has listeners in seven countries, reflecting strong traction among families seeking culturally rooted edutainment.

The team is currently focused on deepening Tamil language storytelling with local heroes and festival-led narratives before expanding across Indian languages and regions. The roadmap doubles down on personalization, safety, and curated content, with the goal of building a joyful, personal story companion that helps children imagine more, learn better, and feel closer to the voices they love.
The StartupTN catalyst effect
What connects these diverse breakthroughs? StartupTN’s TANSEED program. Across Quantic, Diagno, and IppoPay, TANSEED provided early funding, mentorship, and market access that helped translate ideas into impact.

Each company received Rs 10 lakh in funding, while women-led startups and those focused on rural, agritech, and greentech received up to Rs 15 lakh, along with access to a network that opened doors to Fortune 500 partnerships, investor connects, and regulatory support.
Building for what matters
These four startups demonstrate a simple truth: the most enduring innovations solve problems that matter. From preventing workplace fatalities and detecting fractures early to providing dignified credit for small merchants and creating emotionally resonant content for children, Tamil Nadu’s founders are building businesses that serve markets as much as they serve people.

As the state advances toward its $1 trillion economy target by 2030, these ventures represent more than growth metrics. They outline a model of innovation grounded in empathy, built on technology, and scaled with purpose. Together, they prove that Tamil Nadu’s startup ecosystem is not just expanding but evolving in ways that could define the future of Indian entrepreneurship.