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Eagles at Buccaneers prediction: Odds, expert picks, QB matchup, injury update, betting trends, and stats

Eagles at Buccaneers prediction: Odds, expert picks, QB matchup, injury update, betting trends, and stats

It’s a battle of undefeated teams Sunday afternoon in Tampa when the Buccaneers (3-0) host the Philadelphia Eagles (3-0) at Raymond James Stadium.
Tampa blew a 23-6 lead to the Jets after three quarters but rallied late for a 29-27 win despite getting a late field goal attempt blocked and returned for a touchdown. Chase McLaughlin split the uprights from 36 yards with just under two minutes to play to provide the final difference. They are a banged-up team, but with the win Baker Mayfield and co. now sit two games up in the NFC South.
Philly continues to set the pace in the NFC East. Their 33-26 win over the Rams this past weekend also featured a blocked field goal attempt returned for a touchdown. Jordan Davis blocked a last-second 44-yard attempt from Joshua Karty and returned it 61 yards for the clinching score in a 33-26 win for the defending champs. It was actually the second blocked field goal in the game for Philadelphia. Trailing 26-21, Jalen Carter blocked a 36-yard try by Karty at the conclusion of the Rams’ previous possession to spark the comeback.
No doubt special teams will play a role in this one. Lets dive into the matchup and perhaps find an angle or two to attack.
NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts.
Game Details and How to watch the Eagles at Buccaneers live Sunday
Date: Sunday, September 28, 2025
Time: 1:00PM EST
Site: Raymond James Stadium
City: Tampa, FL
Network/Streaming: FOX
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Game odds for the Eagles vs the Buccaneers
The latest odds as of Tuesday courtesy of DraftKings:
Moneyline: Philadelphia Eagles (-198), Tampa Bay Buccaneers (+164)
Spread: Eagles -3.5
Total: 43.5 points
This game opened at Eagles -3 with the Game Total set at 45.5.
Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!
Quarterback Matchup for Philadelphia at Tampa Bay
Eagles Expected Starting QB: Jalen Hurts
Last Game: 9/21 vs. Rams – 21-32 (65.6%), 226yds, 3 TDs, 0 INTs, Sacked 4 times, 9 carries for 40 yards
Season: 3GP, 55-77 (71.4%), 479yds, 3 TDs, 0 INTs, Sacked 7 times, 32 carries for 117 yds
Bucs Expected Starting QB: Baker Mayfield
Last Game: 9/21 vs. Jets – 19-29 (65.5%), 233yds, 1 TD, 0 INTs, Sacked 1 time, 4 carries for 44yds
Season: 3GP, 61-99 (61.6%), 615yds, 6 TDs, 0 INTs, Sacked 6 times, 12 carries for 116yds
Eagles at Buccaneers team stats, betting trends
NFC East teams have won 4 of their last 5 games against NFC South sides
The Eagles have covered the Spread in 4 of their last 5 games against NFC teams
The Eagles’ last 3 games have gone OVER the Total
Neither of these starting quarterbacks has thrown an interception this season
Eagles Player Injuries
RT Lane Johnson (neck) is listed as questionable for Sunday’s game
CB Adoree’ Jackson (groin) is listed as questionable for Sunday’s game
RB/KR Will Shipley (undisclosed) is listed as questionable for Sunday’s game
WR Darius Cooper (shoulder) is listed as questionable for Sunday’s game
QB Tanner McKee (finger) is listed as questionable for Sunday’s game
Buccaneers Player Injuries
WR Mike Evans (hamstring) is listed as doubtful for Sunday’s game
WR Chris Godwin Jr. (knee) is listed as questionable for Sunday’s game
LT Tristan Wirfs (undisclosed) is listed as questionable for Sunday’s game
DE Logan Hall (groin) is listed as questionable for Sunday’s game
S Christian Izien (quad) is listed as questionable for Sunday’s game
DT Calijah Kancey (pectoral) has been placed on IR
Rotoworld Bet Best Bets
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Best bets our model is projecting for this week’s game between the Eagles and the Buccaneers:
Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
Spread: NBC Sports Bet is leaning towards a play ATS on the Tampa Bay Buccaneers at +3.5.
Total: NBC Sports Bet is recommending a play on the over on the Game Total of 43.5.
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