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Dart to Start – Chargers at Giants prediction: Odds, expert picks, QBs, injury update, trends, and stats

Dart to Start - Chargers at Giants prediction: Odds, expert picks, QBs, injury update, trends, and stats

Frustrated Giants’ fans get their wish as rookie Jaxon Dart will replace Russell Wilson as the starting quarterback of the Giants (0-3) Sunday afternoon when New York takes the field against MVP-candidate Justin Herbert and the Los Angeles Chargers (3-0) at MetLife Stadium.
The veteran Wilson’s uneven start to the season (to say the least) coupled with another dismal September for the Giants’ franchise had the natives in the Big Apple growing restless. They needed a reason to pay attention to their team. Enter the rookie out of Ole Miss who gets thrown into the fire against one of the NFL’s top teams in 2025.
Speaking of the Bolts, the expected ground assault from Jim Harbaugh’s troops has yet to materialize but it has not mattered as the Coach and his quarterback Herbert have been more than effective moving the ball through the air. Through three games and three wins, the veteran has thrown for 860 yards including six touchdown passes and just one interception.
Lets take a deeper look at this matchup and possibly find a sweat or two to play along the way.
NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts.
Game Details and How to watch the LA Chargers at New York Giants live Sunday
Date: Sunday, September 28, 2025
Time: 1:00PM EST
Site: MetLife Stadium
City: East Rutherford, NJ
Network/Streaming: CBS
Want to check out the other games on the NFL schedule this week? We’ve got you covered right here on NBC Sports with all the matchup, venue, game-time and TV/streaming info so you won’t miss any of the action!
Game odds for the Chargers vs the Giants
The latest odds as of Tuesday courtesy of DraftKings:
Moneyline: LA Chargers (-298), New York Giants (+240)
Spread: Chargers -6.5
Total: 43.5 points
This game opened at Chargers -6.0 with the Game Total set at 45.5.
Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!
Quarterback Matchup for LA Chargers at New York Giants
Chargers Expected Starting QB: Justin Herbert
Last Game: 9/21 vs. Denver – 28-47 (59.6%), 300yds, 1 TD, 1 INT, Sacked 5 times, 2 carries for 6yds
Season: 3GP, 72-108 (66.7%), 860yds, 6 TDs, 1 INT, Sacked 10 times, 18 carries for 69yds
Giants Expected Starting QB: Jaxon Dart
Last Game: 9/21 vs. Kansas City – 0-0 (0%), 0yds, 0 TDs, 0 INTs, Was not sacked, 1 carry for 3yds
Season: 2GP, 0-0 (0%), 0yds, 0 TDs, 0 INTs, Has yet to be sacked, 2 carries for 0yds
Chargers at Giants team stats, betting trends
The Chargers have won 4 of their last 5 on the road against NFC East teams
The Giants were 3-6 at home against the spread last season
The Chargers’ last 5 games have gone over the Total
Chargers Player Injuries
TE Will Dissly (undisclosed) is listed as questionable for Sunday’s game
RG Mekhi Becton (concussion) is listed as questionable for Sunday’s game
OT Savion Washington (undisclosed) has been declared out for Sunday’s game
RB Najee Harris (Achilles) has been declared out for Sunday’s game
CB Cam Hart (undisclosed) is listed as questionable for Sunday’s game
CB Elijah Molden (undisclosed) is listed as questionable for Sunday’s game
Giants Player Injuries
RB Tyrone Tracy Jr. (shoulder) is listed as doubtful for Sunday’s game
DT Rakeem Nunez-Roches (undisclosed) is listed as questionable for Sunday’s game
LB Darius Muasau (undisclosed) is listed as questionable for Sunday’s game
PK Graham Gano (groin) is listed as questionable for Sunday’s game
DE Chauncey Golston (undisclosed) is listed as questionable for Sunday’s game
LB Demetrius Flannigan-Fowles (undisclosed) is listed as questionable for Sunday’s game
Rotoworld Bet Best Bets
Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.
Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Best bets our model is projecting for this week’s game between the Chargers and the Giants:
Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
Spread: NBC Sports Bet is leaning towards a play ATS on the New York Giants at +6.
Total: NBC Sports Bet is leaning towards a play on the over on the Game Total of 44.0.
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