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It’s a classic matchup of a high-scoring offense taking on a suffocating defense when the Dallas Cowboys (3-3-1) travel to Denver to take on the Broncos (5-2). Coming off a decisive 44-22 win at home over Washington, the Cowboys’ offense is among the most productive in the league. Key offensive numbers: Total offense: 1st in the NFL Scoring offense: 2nd in the NFL Passing offense: 2nd in the NFL Quarterback Dak Prescott is in the midst of an MVP-caliber season, completing over 71% of his passes with 16 touchdowns and only three interceptions. On the other side of the line of scrimmage, however, is a stout Denver defense that leads the NFL in sacks with 34. Prescott has been sacked just 8 times. The biggest question mark for Dallas as always is its defense, which ranks near the bottom of the league in total defense and points allowed. The Broncos are riding an impressive four-game winning streak, placing them at the top of the AFC West for the first time in a decade. Their defense is the driving force behind this resurgence. Defense: Ranks in the top five in points, yards, and EPA allowed. Pass Rush: The Broncos have racked up 34 sacks, eight more than any other team. Second-year quarterback Bo Nix and the Broncos’ offense have been hit or miss this season but last weekend were tremendous in the fourth quarter against the Giants scoring all 33 of its points in the fourth quarter after being shut out for the first three. Lets dive into the matchup and see what the numbers offer us in terms of an advantage or two. NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts. Game Details and How to watch the Cowboys vs. Broncos live Sunday Date: Sunday, October 26, 2025 Time: 4:25PM EST Site: Empower Field at Mile High City: Denver, CO Network/Streaming: CBS Want to check out the other games on the NFL schedule this week? We’ve got you covered right here on NBC Sports with all the matchup, venue, game-time and TV/streaming info so you won’t miss any of the action! Game odds for the Cowboys at the Broncos The latest odds as of Wednesday courtesy of DraftKings: Moneyline: Dallas Cowboys (+150), Denver Broncos (-180) Spread: Broncos -3.5 Total: 50.5 points This game opened at Broncos -3.0 with the Game Total set at 48.5. Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule! Quarterback Matchup for Dallas at Denver Cowboys Starting QB: Dak Prescott Last Game: 10/19 vs. Washington - 21-30, 264yds, 3 TDs, 0 INTs, Sacked 1 time, 5 carries for 7yds rushing Season: 7GP, 185-259, 1,881yds, 16TDs, 3 INTs, Sacked 8 times, 19 carries for 56yds rushing Broncos Starting QB: Bo Nix Last Game: 10/19 vs. Giants - 27-50, 279yds, 2 TDs, 0 INTs, Sacked 2 times, 5 carries for 48yds rushing Season: 7GP, 160-256, 1,556yds, 11TDs, 4 INTs, Sacked 8 times, 38 carries for 172yds rushing Cowboys at Broncos team stats, betting trends The OVER has cashed in 5 of Dallas’ 7 games this season The UNDER has cashed in 5 of Denver’s 7 games this season The Cowboys have covered the Spread in 4 of their last 5 games as a road underdog The Cowboys’ last 4 games have gone over the Total Dallas is 4-3 ATS overall this season Denver is 2-4-1 ATS overall this season Cowboys Player Injuries CB Trevon Diggs (concussion) is questionable for Sunday’s game DE Marshawn Kneeland (ankle) is questionable for Sunday’s game OT Ajani Cornelius (knee) is questionable for Sunday’s game S Juanyeh Thomas (migraine) is questionable for Sunday’s game LB Demarvion Overshown (knee) is expected to practice this week but his status for Sunday is uncertain Broncos Player Injuries LB Jonah Elliss (shoulder) is questionable for Sunday’s game LB Dre Greenlaw (susp.) is suspended for Sunday’s game Rotoworld Bet Best Bets Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700. Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts. Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager. Best bets our model is projecting for this week’s game between the Cowboys and the Broncos: Moneyline: NBC Sports Bet is staying away from a play on the Moneyline. Spread: NBC Sports Bet is leaning towards a play ATS on the Dallas Cowboys at +3. Total: NBC Sports Bet is recommending a play on the over on the Game Total of 49.0. Rotoworld has you covered with all the latest betting info & tools for NFL with player news, game predictions, player props, futures, and trends! 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