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What was originally meant to be a showcase of two elite quarterbacks is down to one, as Jared Goff and the Detroit Lions visit a Washington Commanders team missing quarterback Jayden Daniels. The former LSU star badly injured his elbow in last week's loss to the Seattle Seahawks, meaning it will instead be backup Marcus Mariota under center for Washington. Kickoff from Northwest Stadium is set for 4:25 p.m. ET. The Lions are 8.5-point favorites, per the latest Lions vs. Commanders SportsLine consensus odds. The over/under for total points scored is 49.5. The Lions are -481 money line favorites (risk $481 to win $100), and the Commanders are +363 underdogs (wager $100 to win $363). Before you make any Lions vs. Commanders picks, make sure to check out what the SportsLine Projection Model has to say. Click here to bet Lions vs. Commanders at BetMGM Sportsbook, where new users get either $150 in bonus bets if your first bet wins or up to $1,500 in bonus bets if your first bet loses: Where to bet on Lions vs. Commanders Brand Promo Promo Code DraftKings Bet $5, get $300 in bonus bets if your bet wins + 3 Months of NBA League Pass Just click here bet365 Bet $5, get $200 in bonus bets instantly CBSBET365 BetMGM Up to $1,500 in bonus bets if your first bet loses CBSSPORTS Caesars Bet $1, double your winnings your next 20 bets CBS20X FanDuel Bet $5, get $150 in bonus bets if your bet wins Just click here Fanatics Bet and get up to $2,000 in No Sweat Bets FanCash CBSFAN Where to watch Lions vs. Commanders on Sunday When: Sunday, Nov. 9 Time: 4:25 p.m. ET TV: FOX Stream: Fubo Follow along: CBS Sports App Lions vs. Commanders betting preview Odds: Lions -8.5, over/under 49.5 The loss of Daniels removes a serious amount of sting from Washington's offense. Given the Commanders' defensive struggles, that means it should be even harder to keep up with the high-octane Detroit attack. A few of the Lions' offensive linemen are banged up, which could make things harder for Goff and running backs Jahmyr Gibbs and David Montgomery, but this is still a game the Lions should win. Click here to bet Lions vs. Commanders at FanDuel Sportsbook, where new users get $150 in bonus bets if their first bet of at least $5 wins: Lions vs. Commanders SGP Lions -8.5 (-112) Jahmyr Gibbs Over 71.5 rushing yards (-113) Zach Ertz anytime touchdown scorer (+205) Final odds: +988 at DraftKings (wager $100 to win $988) Model's Lions vs. Commanders score prediction, picks The SportsLine Projection Model has Over 49.5 points hitting in 55% of its simulations despite Daniels being sidelined, likely due to Washington's defensive issues and the fact that Mariota is a capable enough understudy. The Lions win outright in 69% of the sims, but the Commanders offer betting value at heavy plus money. Lions vs. Commanders score prediction: Lions 31, Commanders 22 Want more Week 10 NFL picks?