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The Arizona Cardinals (2-5) travel to Dallas to face the Cowboys (3-4) on Monday Night Football. It is a matchup of two teams who should be desperate for a win after recent struggles. Arizona is coming off their bye week having lost five straight games. Yes, they have been competitive in most, but this is a results-oriented business, and those close games have been losses. While there are rumblings Kyler Murray will see some snaps, Jacoby Brissett is expected to be under center for the majority of the game tonight. The Arizona offense will look to exploit an at-best porous Dallas defense that ranks near the bottom of the league in points and yards allowed, particularly through the air and to tight ends. Looking to overcome that atrocious defense will be the Cowboys’ potent offense, led by Dak Prescott and CeeDee Lamb, who aim to rebound from a blowout loss in Denver last week. Dallas is living on the edge of the playoff chase. A win at home is mandatory to stay at least on that perimeter. Fun Fact: The Cardinals have recently enjoyed success in Dallas, winning their last two in Texas and last three overall. Lets take a deeper dive into this week’s Monday Night Football matchup between the Cardinals and the Cowboys. NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts. Game Details and How to watch the Cardinals at Cowboys live Monday Date: Monday, November 3, 2025 Time: 8:15PM EST Site: AT&T Stadium City: Arlington, TX Network/Streaming: ABC Want to check out the other games on the NFL schedule this week? We’ve got you covered right here on NBC Sports with all the matchup, venue, game-time and TV/streaming info so you won’t miss any of the action! Game odds for the Cardinals at the Cowboys The latest odds as of Monday courtesy of DraftKings: Moneyline: Arizona Cardinals (+150), Dallas Cowboys (-180) Spread: Cowboys -3.5 Total: 53.5 points This game opened at Cowboys -3 with the Game Total set at 53.0. Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule! Quarterback Matchup for Arizona at Dallas Cardinals Expected Starting QB: Jacoby Brissette Last Game: 10/19 vs. Green Bay - 25-36, 279yds, 2TDs, 0INTs, Sacked 6 times, 6 carries for 26yds rushing Season: 4GP, 52-81, 599yds, 4TDs, 1INT, Sacked 8 times, 10 carries for 47yds rushing Cowboys Starting QB: Dak Prescott Last Game: 10/26 at Denver - 19-31, 188yds, 0TDs, 2INTs, Sacked 2 times, 6 carries for 31yds Season: 8GP, 204-290, 2,069yds, 16TDs, 5INTs, Sacked 10 times, 25 carries for 87yds rushing Cardinals at Cowboys team stats, betting trends The Cowboys have won their last 3 games when a home favorite The Cardinals are 8-2 ATS in their last 10 games as a road underdog The Cowboys’ last 3 home games have gone OVER the Total Arizona is 4-3 ATS this season overall Dallas is 4-4 ATS this season overall The Game Total OVER is 6-2 overall in Cowboys’ games this season The Game Total OVER is 4-3 overall in Cardinals’ games this season Cardinals Player Injuries QB Kyler Murray (foot) is questionable for tonight’s game CB Will Johnson (groin) is questionable for tonight’s game CB Garrett Williams (knee) is questionable for tonight’s game DT Walter Nolen III (calf) has been activated off the IR and is questionable for tonight’s game FS Kitan Crawford (undisclosed) is questionable for tonight’s game Cowboys Player Injuries S Juanyeh Thomas (migraine) is questionable for tonight’s game OT Ajani Cornelius (undisclosed) is questionable for tonight’s game C Cooper Beebe (ankle) has been activated from IR and is questionable for tonight’s game S Donovan Wilson (elbow) has been declared OUT for tonight’s game LB Jack Sanborn (groin) has been declared OUT for tonight’s game LB DeMarvion Overshown (knee) has been declared OUT for tonight’s game SS Alijah Clark (ribs) has been declared OUT for tonight’s game Rotoworld Best Bets Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700. Drew Dinsick (@whale_capper): Dallas Cowboys -3 (+109) Selling out to 3 here to support the home team with the better offense. Hoping the Dallas defense isn’t an atrocity the way they were in Week 8. **** Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts. Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager. Best bets our model is projecting for this week’s game between the Cardinals and the Cowboys Moneyline: NBC Sports Bet is staying away from a play on the Moneyline. Spread: NBC Sports Bet is leaning towards a play ATS on the Dallas Cowboys at -3. Total: NBC Sports Bet is recommending a play on the under on the Game Total of 53.5. Rotoworld has you covered with all the latest betting info & tools for NFL with player news, game predictions, player props, futures, and trends! Follow our experts on socials to keep up with all the latest content from the staff: