No. 3 Penn State will put its undefeated record on the line and try to flip the script on reigning Big Ten champion Oregon when it hosts the sixth-ranked Ducks at Beaver Stadium in the annual White Out game Saturday night.
PSU has outscored its three opponents 132-17 over its 3-0 start against Nevada, Florida International and Villanova.
But Oregon, of course, beat Penn State 45-37 in the Big Ten Championship Game last December and is high on the list of favorites for CFP national championship odds.
Here’s a look at the Penn State vs Oregon odds and how to bet.
Penn State vs Oregon odds and best bets
Oregon +3.5 (-110) at FanDuel
Over 51.5 points (-110) at BetMGM
Both teams to score 20-plus points (-122) at FanDuel
Oregon Over 24.5 points (+100) at BetMGM
Penn State Over 27.5 points (-115) at DraftKings
These teams are loaded with offensive talent, and even though each team is in the top 10 in points-against per game, they combined for 82 points in the Big Ten Championship a year ago.
The Ducks (4-0) are averaging 50.8 points per game, and they have topped 34 in every game. They may not win the game, but they’re definitely going to score three-plus touchdowns.
Plus, the Nittany Lions are putting up more than 44 per game — though their opponents have been far inferior to Oregon’s. But Drew Allar, Kaytron Allen and Nicholas Singleton should know what Ducks defensive coordinator Tosh Lupoi will be throwing at them.
*Note: Odds are based on the best value our experts find as of publication; check lines closer to game time to ensure you get the best odds.
Penn State vs Oregon moneyline analysis
Oregon can absolutely win the game, even though Penn State’s implied probability — at FanDuel, which gives the Ducks the best chance of winning — is 60 percent.
But Penn State has won six straight White Out games, including two in 2024. The Nittany Lions are 8-1 in their past nine White Out games, starting, of course, with their stunning three-point win over Ohio State in 2016.
Still, Dan Lanning’s Ducks have rarely been fazed by an intimidating road environment, since they have won eight straight true road games dating back to their 36-33 loss to Washington in Seattle in 2023.
Why Penn State can win as favorites
Best odds: -166 at FanDuel
Score first and play from ahead. The 106,000-plus at Beaver Stadium surely will be loud and raucous, but you can bet there will be some angst — due to James Franklin’s struggles against Oregon, Michigan and Ohio State recently.
Penn State is as talented and experienced a team as there is in FBS. But it has not proven itself capable of being in the class of the above-listed teams, each of which has won a trophy in the past three seasons.
But this is a great shot, since first-year starting quarterback Dante Moore has never played in an environment as he will Saturday night. If the Nittany Lions can put the Ducks behind the 8-ball and play from ahead, it will go a long way to instilling the belief they can win — both in the stands and on the sidelines.
Why Oregon can win as underdogs
Best odds: +145 at DraftKings
If the Ducks can run the ball. For as renowned as Oregon is as a high-octane offense through the years, it has earned that reputation through chunk plays in the running game, rather than the more traditional way of huge passing plays.
True to form, the Ducks are 10th in FBS in rushing yards per game (255.3) and put up 280 yards in their 41-7 rout of rival Oregon State.
For all their success in not giving up points, the Nittany Lions’ run defense has been a little spotty in the season’s early going. PSU has given up 100.7 rushing yards per game.
This is by far the best offensive line the Nittany Lions will face to date. If they can’t stop the run, they have also had trouble rushing the passer, proven by their nine sacks in three games against overmatched opponents — the Ducks could control the clock, stay balanced offensively, and steal the game.