A pair of 3-1 NFC West rivals will kick off Week 5 as the Los Angeles Rams host the San Francisco 49ers on Thursday Night Football. NFL player props figure to center on big names like Matthew Stafford, Christian McCaffrey, Kyren Williams and Puka Nacua, but you may be able to find value with NFL prop lines for under-the-radar players. Brian Robinson Jr. has had a consistent role as McCaffrey’s backup with at least 20 rushing yards in each game. His Thursday Night Football props for rushing have a bar of just 16.5, with NFL prop odds of -114 for the Over.
With the Rams’ defense second in the league with 14 sacks — and with San Fran having uncertainty surrounding Brock Purdy (toe) — the Niners may lean more on the run on TNF. McCaffrey leads the NFL in touches (100), and given the short week, San Francisco may call upon Robinson more than usual, making his NFL prop bet one to consider. Before betting any 49ers vs. Rams props for Thursday Night Football, you need to see the Rams vs. 49ers prop predictions powered by SportsLine’s Machine Learning AI.
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Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine’s Data Science team, AI Predictions and AI Ratings are generated for each player prop.
For 49ers vs. Rams NFL betting on Thursday Night Football, the Machine Learning Model has evaluated the NFL player prop odds and provided Rams vs. 49ers prop picks. You can only see the Machine Learning Model player prop predictions for San Francisco vs. Los Angeles here.
Top NFL player prop bets for 49ers vs. Rams
After analyzing the Rams vs. 49ers props and examining the dozens of NFL player prop markets, the SportsLine’s Machine Learning Model says Rams QB Stafford goes Over 232.5 passing yards (-114 at FanDuel). Stafford is averaging 278.5 passing yards on the season as he ranks second in passing yards entering Week 5. He’s had at least 245 yards in three of four starts, in addition to having at least 243 passing yards in six of his last seven home starts dating back to last year’s regular season.
Stafford should have little deterrence from San Fran’s defense, as the Niners’ current 11-game streak without an interception is tied for the longest by any NFL team since 1940. With Nick Bosa (knee) out for the year, the 49ers had zero sacks last week, and a lack of pass rush will allow wideouts like Nacua and Davante Adams to run free in the secondary. The model projects Stafford to have 279 passing yards, giving this prop bet a 4.5-star rating. See more NFL props here.
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How to make NFL player prop bets for Rams vs. 49ers
In addition, the SportsLine Machine Learning Model says another star sails past his total and has nine additional NFL props that are rated four stars or better. You need to see the Machine Learning Model analysis before making any 49ers vs. Rams prop bets for Thursday Night Football.