Health

New Covid variant ‘evades antibodies’ as WHO lists it as ‘of interest’

By Ben Hurst

Copyright glasgowlive

New Covid variant 'evades antibodies' as WHO lists it as 'of interest'

The World Health Organisation (WHO) has flagged a new variant of Covid as ‘of interest’ which demonstrates concerning resistance to antibodies. The organisation classified the BA.3.2 strain of Covid as one it intends to ‘closely monitor’ in a statement today and it’s already been identified in Europe.

The WHO characterised it as a ‘potentially emerging’ variant which could become widespread. Presently the WHO is collecting data for vaccine producers to utilise in combating the latest mutations this winter, when infections are anticipated to surge.

The UK Health Security Agency has stated that the two most prevalent current variants are the XFG and NB. 1.8.1 – occasionally called the Stratus and Nimbus variants. Should the BA, reports the Mirror.

3.2 mutation which hasn’t received a name yet arrive in the UK it’s recognised to ‘evade’ antibodies and consequently is more hazardous for transmission in communities which have been vaccinated.

A study in the medical Lancet journal earlier this year stated: “Our findings suggest that BA.3.2 (A) and BA.3.2 (B) might enter cells slightly less efficiently than the parental BA.3 variant; however, BA.3.2 (A) and BA.3.2 (B) might be able to evade the neutralising antibodies used for COVID-19 therapy or those induced by vaccination with a markedly higher efficiency.

“The evasion of antibodies by the variants in individuals vaccinated with the JN.1-booster vaccine was similar to, or greater than, that observed for the currently dominating LP8.1.1 variant. These observations suggest that BA.3.2-particularly BA.3.2 (B)-may disseminate within populations with high antibody levels, thereby warranting close monitoring.”

The report also mentioned that earlier this year a ‘highly mutated’ descendant of the omicron subvariant BA. 36 was detected in South Africa.

It continued: “In April, 2025, the variant, designated as BA.3.2, was also detected in the Netherlands, raising the possibility of global dissemination. BA.3.2 harbours more than 50 S protein mutations compared with BA.3 (appendix pp 2, 13), which might have profoundly altered the cell entry and antibody-mediated neutralisation of BA.3.2. “.

The new strain, known as Stratus, has two variants, XFG and XFG. 3, with some experts suggesting that the variant is known for its unique symptom of giving people a hoarse voice.

Despite accounting for a large proportion of new cases, experts are not overly concerned about the spread, noting it is normal for viruses to mutate and change.

The UK Health Security Agency (UKHSA) has provided an update on the current Covid-19 variants in circulation across the country. “The most common current variants are the XFG and NB.1.8.1 (sometimes referred to in the media as the Stratus and Nimbus variants). Our genomic surveillance of SARS-CoV-2 lineages last month found that 35% were classified as XFG.3, 28% were classified as XFG, 11% were classified as NB.1.8.1, 7% were classified as XFG.5 and 7% were classified as XFG.3.4.1.

“Current data does not indicate that these variants lead to more severe illness than other variants in circulation.

“It’s normal for viruses to mutate and change, and as more data becomes available on these variants we’ll have a better understanding of how they interact with our immune systems and how to optimise our protection, as well as actions we can take to keep the most vulnerable safe and live our lives as normally as possible. The most important thing is for those eligible to get their vaccination when it is due.”

The UKHSA has also issued advice this week on what steps individuals should take if they suspect they have contracted Covid-19.

It advised: “If you have symptoms of a respiratory infection, such as COVID-19, and you have a high temperature or do not feel well enough to go to work or carry out normal activities, you should avoid contact with vulnerable people and stay at home if possible.

“For those of us who absolutely can’t stay at home, the Living with COVID guidance remains unchanged, and will reduce the chance of passing on your infection to others:

Wear a well-fitting face covering made with multiple layers or a surgical face mask Avoid crowded places such as public transport, large social gatherings, or anywhere that is enclosed or poorly ventilated Take any exercise outdoors in places where you will not have close contact with other people Cover your mouth and nose when you cough or sneeze; wash your hands frequently with soap and water for 20 seconds or use hand sanitiser after coughing, sneezing and blowing your nose and before you eat or handle food; avoid touching your face “